السبت، 22 مارس 2014

Microalbumin - Creatinine Ratio

Microalbumin - Creatinine Ratio:

Microalbumin/Creatinine Ratio

The microalbumin test is an early indicator of kidney failure. It measures the tiny amounts of albumin that the body begins to release into the urine several years before significant kidney damage becomes apparent. Albumin is a protein that is produced in the liver.

It is present in high concentrations in the blood, but when the kidneys are functioning properly, virtually no albumin is allowed to leak through into the urine. If a person’s kidneys become damaged or diseased, however, they begin to lose their ability to filter proteins out of the urine. This is frequently seen in chronic diseases, such as diabetes and hypertension, with increasing amounts of protein in the urine reflecting increasing kidney failure.
Creatinine, a byproduct of muscle metabolism, is normally excreted into the urine on a consistent basis. Its level in the urine is relatively stable. Since the concentration (or dilution) of urine varies throughout the day, this property of creatinine allows its measurement to be used as a corrective factor in random/spot urine samples. When a creatinine measurement is performed along with a random microalbumin, the result is the microalbumin/creatinine ratio (also called the albumin/creatinine ratio (ACR)), which the American Diabetes Association states is the preferred test for screening for microalbuminuria

The test used to

get screened for a possible kidney disorder or for early damage to the kidneys in those with diabetes

the way of sample obtaining

24-hour urine sample

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